A review of rifaximin and bacterial overgrowth in poorly responsive celiac disease

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A review of rifaximin and bacterial overgrowth in poorly responsive celiac disease.

A proportion of patients with celiac disease have a poor response to a gluten-free diet, which may be due to small-intestinal bacterial overgrowth (SIBO). Treatment with rifaximin is often used in the clinical setting, but there is limited literature to support this practice. In addition, challenges in the diagnosis of SIBO confound response interpretation. Our recent placebo-controlled trial d...

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Partially responsive celiac disease resulting from small intestinal bacterial overgrowth and lactose intolerance

BACKGROUND Celiac disease is a common cause of chronic diarrhea and malabsorption syndrome all over the world. Though it was considered uncommon in India in past, it is being described frequently recently. Some patients with celiac disease do not improve despite gluten free diet (GFD). A study described 15 cases of celiac disease unresponsive to GFD in whom small intestinal bacterial overgrowth...

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Chronic prostatitis and small intestinal bacterial overgrowth: effect of rifaximin.

INTRODUCTION This pilot study determined the efficacy of rifaximin, a gut-directed antibiotic, in reducing chronic prostatitis (CP) and gastrointestinal (GI) symptoms in patients with CP type III. The prevalence of small intestinal bacterial overgrowth (SIBO) and irritable bowel syndrome (IBS) in patients with CP was also evaluated. MATERIALS AND METHODS Chronic prostatitis patients were recr...

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Antibiotic therapy in small intestinal bacterial overgrowth: rifaximin versus metronidazole.

BACKGROUND AND OBJECTIVES Few controlled trials on antibiotic therapy for small intestinal bacterial overgrowth are available at present. Aim of the study was to assess efficacy, safety and tolerability of rifaximin with respect to metronidazole for the treatment of small intestinal bacterial overgrowth. MATERIAL AND METHODS We enrolled 142 consecutive patients with diagnosis of small intesti...

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Should Small Intestine Bacterial Overgrowth be Ruled out as a Cause of Non-Responsive Celiac Disease?: A Case Report

Non-responsive celiac disease is defined as the persistency of symptoms, signs or laboratory abnormalities typical of CD despite 6-12 months of dietary gluten avoidance. Small intestine bacterial overgrowth has been classically considered a potential cause for non-responsive celiac disease. Nevertheless, the evidence regarding its prevalence among non-responsive celiac patients is conflicting, ...

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ژورنال

عنوان ژورنال: Therapeutic Advances in Gastroenterology

سال: 2011

ISSN: 1756-2848,1756-2848

DOI: 10.1177/1756283x11422264